Carcinoma ex-pleomorphic adenoma derived from recurrent pleomorphic adenoma shows important difference by array CGH compared to recurrent pleomorphic adenoma without malignant transformation
نویسندگان
چکیده
منابع مشابه
Carcinoma ex-pleomorphic adenoma derived from recurrent pleomorphic adenoma shows important difference by array CGH compared to recurrent pleomorphic adenoma without malignant transformation.
INTRODUCTION A key step of cancer development is the progressive accumulation of genomic changes resulting in disruption of several biological mechanisms. Carcinoma ex-pleomorphic adenoma (CXPA) is an aggressive neoplasm that arises from a pleomorphic adenoma. CXPA derived from a recurrent PA (RPA) has been rarely reported, and the genomic changes associated with these tumors have not yet been ...
متن کاملSquamous cell carcinoma ex pleomorphic adenoma a case report
A rare case of squamous cell carcinoma ex pleomorphic adenoma in maxillary sinus is presented. The patient is a 50-year-old woman presenting with a slow-progressive swelling in left side of her face that she has noticed 2 years earlier. The lesion was not painful and caused asymmetry and mild exophthalmos. Microscopic examination revealed that the tumor was composed of two components partly of ...
متن کاملRecurrent Pleomorphic Adenoma of the Parotid Gland
This is a retrospective analysis of 35 patients treated for a first recurrence of pleomorphic adenoma of the parotid gland from 1982 to 1997. All patients were treated surgically; no patient received radiotherapy for benign disease. We experienced a locoregional control rate of 77%. Our malignant transformation rate was 5.7%. Our results suggest that in carefully selected patients, local excisi...
متن کاملClinical Manifestations of Recurrent Parotid Pleomorphic Adenoma
OBJECTIVES This study was undertaken to confirm the clinical characteristics of recurrent pleomorphic adenoma (RPA), and to identify those factors that affect the development of malignant transformation (MT) from RPA. METHODS The medical records of 270 patients, who were operated upon for parotid PA, were retrospectively reviewed. The pathologic specimens of a selected series of 23 patients w...
متن کاملCarcinoma ex-pleomorphic adenoma -- a giant tumor.
Pleomorphic adenoma is one of the most frequent tumors that involve the parotid gland. The tumor constantly increases in dimension if not cured in due time and may become malignant. A case of a patient suffering from a carcinoma ex-pleomorphic adenoma that had a 20-year-evolution and reached impressive dimensions is presented. The tumor holds the second place worldwide among the largest carcino...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Brazilian Journal of Otorhinolaryngology
سال: 2016
ISSN: 1808-8694
DOI: 10.1016/j.bjorl.2015.12.004